Over 60: Your dosage will probably be quite a bit below the average.
Pregnancy: If you're pregnant or planning to become pregnant, avoid ibuprofen. There are special risks during the last trimester. It should also be avoided during breast feeding.
Children: (see above).
Other concerns: Because of possible stomach problems, avoid alcohol when taking ibuprofen. You should also avoid it for at least 3 days before surgery, because of the way it effects your blood.
It's a good idea to take ibuprofen with food, or at least milk.
For more on ibuprofen dosage, read the Medline Plus information here .
1 Deutsche Gesellschaft für Ernährung, Österreichische Gesellschaft für Ernährung, Schweizerische Gesellschaft für Ernährungsforschung, Schweizerische Vereinigung für Ernährung (Hrsg.) „Referenzwerte für die Nährstoffzufuhr“ 1. Auflage, 5., korrigierter Nachdruck, DGE, Bonn 2013 http:///?name=Content&pa=showpage&pid=3&page=7
3 Mustafa Vakur Bor, Kristina M von Castel-Roberts, Gail PA Kauwell, Sally P Stabler, Robert H Allen, David R Maneval, Lynn B Bailey Ebba Nexo „Daily intake of 4 to 7 µg dietary vitamin B-12 is associated with steady concentrations of vitamin B-12–related biomarkers in a healthy young population“ Am J Clin Nutr 2010 91: 3 571-577; First published online January 13, 2010. doi:/.
4 Berlin, H., Berlin, R. and Brante, G. (1968), ORAL TREATMENT OF PERNICIOUS ANEMIA WITH HIGH DOSES OF VITAMIN B12 WITHOUT INTRINSIC FACTOR. Acta Medica Scandinavica, 184: 247–258. doi: /-
5 ANDRÈS, E., DALI-YOUCEF, N., VOGEL, T., SERRAJ, K. and ZIMMER, J. (2009), Oral cobalamin (vitamin B12) treatment. An update. International Journal of Laboratory Hematology, 31: 1–8. doi: /-
6 Barbara M Rhode et al. Treatment of Vitamin B12 Deficiency after Gastric Surgery for Severe Obesity. Obesity Surgery May 1995, Volume 5, Issue 2, pp 154-158
7 C. Poitou Bernert, C. Ciangura, M. Coupaye, S. Czernichow, . Bouillot, A. Basdevant, Nutritional deficiency after gastric bypass: diagnosis, prevention and treatment, Diabetes & Metabolism, Volume 33, Issue 1, February 2007, Pages 13-24, ISSN 1262-3636, http:////.
8 Eussen SM, de Groot LM, Clarke R, et al. Oral Cyanocobalamin Supplementation in Older People With Vitamin B12 Deficiency: A Dose-Finding Trial. Arch Intern Med. 2005;165(10):1167-1172. doi:/.
9 Sharabi, A., Cohen, E., Sulkes, J. and Garty, M. (2003), Replacement therapy for vitamin B12 deficiency: comparison between the sublingual and oral route. British Journal of Clinical Pharmacology, 56: 635–638. doi: /-
10 Georges Delpre, Pinhas Stark, Yaron Niv, Sublingual therapy for cobalamin deficiency as an alternative to oral and parenteral cobalamin supplementation, The Lancet, Volume 354, Issue 9180, 28 August 1999, Pages 740-741, ISSN 0140-6736, http:////S0140-6736(99)02479-4.
Administration advice :
-Extended/controlled/prolonged/sustained release tablet formulations should not be crushed or chewed.
-Take with food to decrease gastrointestinal side effects.
-This drug should be taken as the same time(s) each day.
Storage requirements :
-The manufacturer product information should be consulted.
-Lithium toxicity is related to serum lithium levels, and may occur at doses close to therapeutic levels.
-Patients in the manic phase are better able to tolerate lithium; tolerance to lithium decreases when manic symptoms subside.
-Mania is characterized by pressure of speech, motor hyperactivity, reduced sleep requirements, flight of ideas, grandiosity, elation, poor judgment, aggressiveness, and/or hostility. Maintenance therapy reduces the frequency of manic episodes and diminishes the intensity of the episodes.
-ECG, especially in patients at risk of unmasking Brugada syndrome
-Thyroid function, especially in patients with thyroid disorders
-Renal function tests (., urinalysis, urine specific gravity, serum creatinine, creatinine clearance), especially in patients who develop polyuria and/or polydipsia
Patient advice :
-Patients should be told to seek immediate medical attention if signs/symptoms of Brugada syndrome, encephalopathic syndrome, or diabetes insipidus occur.
-Patients, family members, and/or caregivers should be instructed to discontinue therapy and immediately report any signs/symptoms of lithium toxicity, change in behavior, or suicidality.
-Inform patients that this drug may cause drowsiness, and they should avoid driving or operating machinery until the full effects of the drug are seen.
-Patients should be counseled on the importance of maintaining adequate salt and water intake.
-Advise patients to speak to their healthcare provider if they become pregnant, intend to become pregnant, or are breastfeeding.