In males with delayed puberty: Various dosage regimens have been used; some call for lower dosages initially with gradual increases as puberty progresses, with or without a decrease to maintenance levels. Other regimens call for higher dosage to induce pubertal changes and lower dosage for maintenance after puberty. The chronological and skeletal ages must be taken into consideration, both in determining the initial dose and in adjusting the dose. Dosage is within the range of 50 to 200 mg every 2 to 4 weeks for a limited duration, for example, 4 to 6 months. X-rays should be taken at appropriate intervals to determine the amount of bone maturation and skeletal development (see INDICATIONS AND USAGE and WARNINGS ).
The next study we’re going to look at is how BCAA supplementation help preserves muscle in times of weight loss or muscle wasting conditions or diseases. This study looked at BCAA supplementation in patients with liver cirrhosis . Dr. Willis Maddrey looked at how BCAA supplementation effected nitrogen retention of those with severe liver disease . The group was split into two, one half were given an intravenous (IV) solution at night enriched with BCAAs and the other half, the control group, placebo. Nitrogen balance improved in those supplementing BCAAs compared to the control, which translates to muscle being spared overnight and not used for energy. Again, the BCAAs were shown to be anti-catabolic in this instance.