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Medicines are sometimes prescribed for conditions that are not mentioned in patient information leaflets. Do not use CLOBEX® Shampoo (clobetasol propionate shampoo) for a condition for which it was not prescribed. Do not give CLOBEX® Shampoo (clobetasol propionate shampoo) to other people, even if they have the same symptoms you have. It may harm them. This leaflet summarizes the most important information about CLOBEX® Shampoo (clobetasol propionate shampoo) . If you would like more information, talk with your doctor. You can ask your pharmacist or doctor for information about CLOBEX® Shampoo (clobetasol propionate shampoo) that is written for health professionals.

Betamethasone dipropionate (Diprolene; Diprolene AF; [Diprosone and Alphatrex have been discontinued]) is a corticosteroid topical medication prescribed for relief of inflammation and itching associated with a variety of skin conditions for example:

  • atopic dermatitis ,
  • contact dermatitis ,
  • plaque psoriasis , and
  • allergic dermatitis .
Side effects, drug interactions , dosing information, and patient safety information should be reviewed prior to taking any medication.

Detection of halotestin and other such illegal anabolic steroids in sports is achieved by GS-MS identification of urinary excreted anabolic steroids and their metabolites. In a test for halotestin, a dry residue obtained from a urine sample is dissolved in dimethylformamide and a sulfur trioxide-pyridine complex and is heated with 1% potassium carbonate solution. Halotestin and many of its metabolites contain two polar hydroxyl groups, leading to intermolecular hydrogen bonding that increases their boiling point and reduces volatility. In order to attain a gaseous sample for GC-MS, the products of hydrolysis are extracted, dissolved in methanol and derivatised to form volatile trimethylsilyl (TMS) esters by adding N -methyl- N -trimethylsilyl-trifluoroacetamide (MSTFA) and trimethylsilylimidazole (TMSImi). [18]

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