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Because it has some selectivity for cerebral vasculature, nimodipine's main use is in the prevention of cerebral vasospasm and resultant ischemia , a complication of subarachnoid hemorrhage (a form of cerebral bleed ), specifically from ruptured intracranial berry aneurysms irrespective of the patient's post-ictus neurological condition. [2] Its administration begins within 4 days of a subarachnoid hemorrhage and is continued for three weeks. If blood pressure drops by over 5%, dosage is adjusted. There is still controversy regarding the use of intravenous nimodipine on a routine basis. [1] [3]

Kleschick, W. A.; Carson, C. M.; Costales, M. J.; Doney, J. J.; Gerwick, B. C.; Holtwick, J. B.; Little, J. C.; Meikle, R. W.; Monte, W. T.; Pearson, N. R.; Snider, S. W.; Subramanian, M. V.; VanHeertum, J. C.; Vinogradoff, A. P., “1,2,4-Triazolo[1,5-a]pyrimidine-2-sulfonanilide Herbicides. The Influence of Alkoxy Heterocyclic Substitution on the In Vitro and In Vivo Biological Activity and Soil Decomposition.” In Synthesis and Chemistry of Agrochemicals III ; Baker, D. R.; Fenyes, J.; Steffens, J. J., Eds.; ACS Symposium Series 504, American Chemical Society: Washington, ., 1992, p. 17-25.

BVCPL is a privately held company incorporated in the state of Gujarat, Vadodara in 1996, Best Value Chem (P) Limited is engaged in manufacturing of Aroma Chemicals. Increased volumes and widened product range called for bigger and sophisticated production facility & therefore in 2000, a new plant was commissioned at Karakhadi – 50 Kms from Vadodara, Gujarat. BVCPL's increasing business lead to another operational plant at Moxi – 30 Kms from Vadodara, a higher capacity plant to take care of the international clients. Today export Market covers around 80% of total BVCPL's sales.

Propionate aldol

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